About Cushing's

Endogenous Cushing’s syndrome is a rare condition caused by too much cortisol in your body. “Endogenous” means that something inside your body causes too much cortisol production.

The most common form of Cushing’s syndrome is Cushing’s disease, which is caused by a tumor in the pituitary gland (a gland under the brain that produces and controls hormones). When you see “Cushings’s” on this website, it includes both Cushing’s syndrome and Cushing’s disease.
The most common form of Cushing’s syndrome is Cushing’s disease, which is caused by a tumor in the pituitary gland (a gland under the brain that produces and controls hormones). When you see “Cushings’s” on this website, it includes both Cushing’s syndrome and Cushing’s disease.

If you have been diagnosed with Cushing’s and are experiencing symptoms, ask your doctor if Recorlev® (levoketoconazole) may be right for you.

Cortisol is a hormone made by the adrenal glands—located on top of the kidneys—that plays an important role in the way your body functions, including:

Responding to stress
Controlling blood pressure
Changing protein, carbohydrates, and fat into energy
Changing protein, carbohydrates, and fat into energy

Irregular cortisol production can affect your entire body, including your bones and your immune, cardiovascular, and nervous systems.

The main goal of treating Cushing’s is to get your cortisol levels back to normal

Why is it important to control your cortisol levels?

Too much cortisol in your body caused by Cushing’s can be difficult to live with and may affect your overall health and quality of life

The impact of too much cortisol is both physical and emotional, and it may lead to:
Weight gain
Depression and feeling irritable
Irregular periods
Poor concentration
Fatigue

Talk to your doctor about the chances of an increase in testosterone from your medicine.